Search Strains

n4827 is a null allele of gcn-1 and that loss of gcn-1 function causes a defect in M4 sister cell death. Reference: Hirose T & Horvitz HR. PLoS Genet. 2014 Aug 7;10(8):e1004512.

Unc. Abnormal cell death. Cells that normally die survive.

Sister cells of NSM and I2 neurons fail to undergo programmed cell death. Other cell deaths unaffected. Semi-dominant.

n1165 blocks cell death. Temperature sensitive Egl. Semi-dominant Egl.

Animals heterozygous for the duplication are WT. Animals which have lost the duplication are Unc. Animals homozygous for the duplication are viable. They are small, sickly Egl worms which don't give rise to Uncs.

Absence of cell death. Strong allele.

Small. Unc. Muv.

Unc. Egl. Transformation of sex myoblasts into body wall muscle.

Dpy. Egl. Transformation of sex myoblasts into body wall muscle.

Absence of cell death. See WBG 10(1):31.

Small. Egl. Slow growing.

Egl. Maintain under normal conditions. Reference: DeVore DL, et al. Cell. 1995 Nov 17;83(4):611-20.

Egl. Maintain under normal conditions. Reference: DeVore DL, et al. Cell. 1995 Nov 17;83(4):611-20.

Temperature sensitive Multi-vulva. Slow growing. Unc-coils, jerky going backward. Small.

Unc. Abnormal cell death.

Unc. Abnormal cell death.

Vulvaless. Isolated in lin-8(n111); this strain may still contain n111.

Pick DpyUnc worms to maintain, as e1913 is a dominant Unc and a recessive lethal. Actually, the Uncs are not very Dpy, so pick non-Dpy-looking animals that don't move well. e1913 previously called unc-110.

Dpy. Persistent cell corpses. Maternal effect. Recessive.

Persistent cell corpses. Maternal effect. Recessive.

Heterozygotes are mostly non-Muv (about 20% will be Muv because n1700 is semi-dominant) and non-Unc. Hets segregate Twitchers which die at various larval stages or as Vul adults, because of the maternal effect rescue of n1531 by n1700. The Twitchers will not give viable progeny. Hets also segregate DpyMuvs. The strain segregates males which will mate, though not very well.

Dominant maternal effect. Survival of cells which normally undergo programmed cell death.

Small. Vulvaless (temperature sensitive-91% Vul at 15C and 100% Vul at 20C and 25C). n1490 is also temperature sensitive Unc.

Maintain at 15C. glp-1(q231) is temperature sensitive. Unc. ced-7(n1892) causes persistent cell corpes and has a maternal effect.

Cell corpses unengulfed.

Unengulfed cell corpses.

Cell corpses persist. Unc. n1892 is the strongest allele of ced-7.

n1993: cell corpses unengulfed.

Cell corpses unengulfed.

Dpy. Unc. Abnormal Cell Death.

ced-7(n1892): strongest allele, cell corpses persist.

Cell corpses unengulfed.

Persistent cell corpses. Maternal effect. Recessive.

ced-10(n1993): cell corpses unengulfed. Long.

Persistent cell corpses. Maternal effect. Recessive.

Cell corpses unengulfed. Strong allele.

Cell corpses unengulfed.

Dpy. Maternal effect persistent cell corpses.

Small. Maternal effect persistent cell corpses.

Unc. Persistent cell corpses-Maternal effect.

Engulfment of cell corpses defective. Zygotic recessive.

Cell corpses unengulfed.

Persistent cell corpses.

Sister cells of NSM neurons fail to undergo programmed cell death. Other cell deaths unaffected. 60% penetrance at 25C; 10% penetrance at 15C.

Con, Sup, Dec (temperature-sensitive). Reference: Mol Bio Cell (2005) 16:1355-65.

Dpy (ts). Unc. Abnormal cell death. Cells that normally die survive.

Small. Slightly jerky movement. Terminal bulb relaxation defective. Egl-c. Cold-sensitive Pat.

Unc. Null allele of unc-76.

Dpy. Temperature sensitive Muv. Abnormal cell death.

Maintain by picking wild-type animals raised at 25C. Heterozygotes will be wild-type and segregate wild-type, Unc, and Sterile Muv. The phenotype of homozygous lin-13 hermaphrodites segregating from a heterozygous mother depends on the temperature at which the strain was grown. At 25C, homozygous hermaphrodites segregating from a heterozygote are both Muv and sterile. At 20C, ~1/2 of hermaphrodites segregating from a heterozygote are sterile, but only a few are Muv. At 15C, hermaphrodites segregating from a heterozygote are almost wild type in appearance and fertility. However, if the progeny of these 15C animals are grown at 15C, all are sterile and some are Muv. If the progeny of these 15C animals are grown at 25C, then some animals arrest during larval growth and the rest are both sterile and Muv. Reference: Ferguson EL & Horvitz HR. Genetics. 1985 May;110(1):17-72. PMID: 3996896.