Unc-paralysed, kinky, small, irregular pharyngeal pumping. Suppressed by sup-5 and sup-7.

Slightly Unc. Suppressed by sup-5 and sup-7. Null allele?

Slightly Unc. Suppressed by sup-5 and sup-7. Null allele?

Aldicarb resistant. This allele is a small exonic deletion that frameshifts exon 21, thus deleting the MUN domain of both long and short isoforms of unc-13. The reference allele e51 is R471-stop, affecting only UNC-13L. Derived by 2x outcross of BC168. Reference: Rose AM & Baillie DL. Genetics. 1980 Nov;96(3):639-48.

The origin of this strain is KR1082 via CB51. KR1082 was maintained on plates for a period of approximately two years. After this time, DNA was made and the Tc1 pattern examined. The number of Tc1s found in KR1787 was greater than that found in KR1082. Perhaps as many as 30 additional Tc1s were visible in excess of those normally seen in N2 strains.

Unc. See WBPaper00003781.

NL subclone of KR1787. NL received strain KR1787 from Ann Rose 11/93. High copy Tc1 strain. See WBG 14(4): 16-17.

Animals heterozygous for the duplication are WT. Animals which have lost the duplication are Unc. Animals homozygous for the duplication are viable. They are small, sickly Egl worms which don't give rise to Uncs.

jsIs1 [(pSB120) snb-1::GFP + rol-6(su1006)]. Roller Unc.

Heterozygotes are WT and segregate WT, hT1 homozygotes (mid-larval lethals), md2415 homozygotes (generally L1 lethals which are almost completely paralyzed and have a coily posture with some head movement), and dead eggs. md2415 has a 2.7 kb deletion in the "unc-13R" region.

Unc. Reduced brood size. Larval lethal, larval arrest. Steriles. Bursts at vulva. Can be maintained as a homozygote.

ddi-1 also known as vsm-1.

Paralysed Unc.

Strain gives WT hermaphrodites and dead eggs.

Unc. Temperature-sensitive Dpy. Grows best at 15C.

Unc and Vul.

Dpy. Unc.

Paralyzed Unc. This strain carries a tightly linked mutation, che-3(ky1018), that changes Q1107 of che-3 to a stop codon. Reference: Larsch, et al. (2015) Cell Reports.

Unc. See WBPaper00003781 regarding the unc-122 mutation.

Temperature sensitive dauer constitutive. Unc. Semi-paralyzed. Closely linked.

Dpy. Unc.

sup-7 suppresses unc-13. Movement not WT. Fertility is low. Grows between 22.5C and 24C.

Temperature sensitive. Grow at permissive temperature of 15C. Fully penetrant cytokinesis defect at the restrictive temperature of 25C. Semi-dominant Unc.

Animals with the Dup are Unc. Animals which have lost the Dup are DpyUnc and arrest in late larval development. See also WBPaper00005456.

Animals with the Dup are Unc. Animals which have lost the Dup are DpyUnc and arrest in late larval development.

Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h91 arrests as a late larva or sterile adult). Maintain by picking Unc-13 and checking for correct segregation of progeny.

Animals with the duplication are Unc. Animals which have lost the duplications are DpyUncLet (Sterile adults). Maintain by picking Unc non-Dpy.

Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h88 arrests as an early larva). Maintain by picking Unc-13 and checking for correct segregation of progeny.

Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h87 arrests as a mid-late larva). Maintain by picking Unc-13 and checking for correct segregation of progeny.

Animals with the Dup are Unc.Animals which have lost the Dup are DpyUnc and arrest in early larval development.

Animals with the Dup are Unc. Animals which have lost the Dup are DpyUnc and arrest in early larval development.

Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h104 arrests as a sterile adult). Maintain by picking Unc-13 and checking for correct segregation of progeny.

Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h112 arrests as a mid-stage larva). Maintain by picking Unc-13 and checking for correct segregation of progeny.

Animals with the Dup are Unc. Animals which have lost the Dup arrest as embryos to early larvae.

Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest as Sterile adults.

Unc-13 phenotype. h281 arrests as an embryo. Pick Unc-13 animals to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.

Animals with the Dup are Unc. Animals which have lost the Dup are DpyUncLet. Lethal->Sterile adult.

Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h316 arrests as an embryo or early larva). This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.

Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h392 arrests as a mid-stage larva). Pick Unc-13 animals to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.

Unc-13 phenotype. h402 arrests as an embryo. Pick Unc-13 animals to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.

Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early/mid larval development.

Unc.

Unc. Egl. Transformation of sex myoblasts into body wall muscle.

Unc. Abnormal cell death.

ccIs55 [unc-54::lacZ + sup-7(st5)] V. Unc.

Previously called MA1128.