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Strain Species Genotype
CB1091 C. elegans unc-13(e1091) I. Show Description
Unc-paralysed, kinky, small, irregular pharyngeal pumping. Suppressed by sup-5 and sup-7.
CB312 C. elegans unc-13(e312) I. Show Description
Slightly Unc. Suppressed by sup-5 and sup-7. Null allele?
CB376 C. elegans unc-13(e376) I. Show Description
Slightly Unc. Suppressed by sup-5 and sup-7. Null allele?
EG9631 C. elegans unc-13(s69) I. Show Description
Aldicarb resistant. This allele is a small exonic deletion that frameshifts exon 21, thus deleting the MUN domain of both long and short isoforms of unc-13. The reference allele e51 is R471-stop, affecting only UNC-13L. Derived by 2x outcross of BC168. Reference: Rose AM & Baillie DL. Genetics. 1980 Nov;96(3):639-48.
KR1787 C. elegans unc-13(e51) I. Show Description
The origin of this strain is KR1082 via CB51. KR1082 was maintained on plates for a period of approximately two years. After this time, DNA was made and the Tc1 pattern examined. The number of Tc1s found in KR1787 was greater than that found in KR1082. Perhaps as many as 30 additional Tc1s were visible in excess of those normally seen in N2 strains.
MT7929 C. elegans unc-13(e51) I. Show Description
Unc. See WBPaper00003781.
MT8004 C. elegans unc-13(n2813) I. Show Description
NL1787 C. elegans unc-13(e51) I. NL subclone of KR1787. Show Description
NL subclone of KR1787. NL received strain KR1787 from Ann Rose 11/93. High copy Tc1 strain. See WBG 14(4): 16-17.
MT2936 C. elegans unc-13(e51) I; nDp4 (I;V)/+. Show Description
Animals heterozygous for the duplication are WT. Animals which have lost the duplication are Unc. Animals homozygous for the duplication are viable. They are small, sickly Egl worms which don't give rise to Uncs.
RK1 C. elegans unc-13(e323) I; jsIs1. Show Description
jsIs1 [(pSB120) snb-1::GFP + rol-6(su1006)]. Roller Unc.
RM2431 C. elegans unc-13(md2415)/hT1 I; +/hT1 V. Show Description
Heterozygotes are WT and segregate WT, hT1 homozygotes (mid-larval lethals), md2415 homozygotes (generally L1 lethals which are almost completely paralyzed and have a coily posture with some head movement), and dead eggs. md2415 has a 2.7 kb deletion in the "unc-13R" region.
AG165 C. elegans san-1(av31) unc-13(e450) I. Show Description
Unc. Reduced brood size. Larval lethal, larval arrest. Steriles. Bursts at vulva. Can be maintained as a homozygote.
AMH61 C. elegans unc-13(e51) I; ddi-1(ok1468) IV. Show Description
ddi-1 also known as vsm-1.
BC455 C. elegans unc-15(e73) unc-13(e51) I. Show Description
Paralysed Unc.
BS585 C. elegans unc-13(e51) ozDf5 I; nDp4 (I;V)/+. Show Description
Strain gives WT hermaphrodites and dead eggs.
BW1053 C. elegans dpy-14(e188) unc-13(e1091) I. Show Description
Unc. Temperature-sensitive Dpy. Grows best at 15C.
BW538 C. elegans unc-13(e1091) lin-10(e1438) I. Show Description
Unc and Vul.
CB2167 C. elegans dpy-5(e61) unc-13(e1091) I. Show Description
Dpy. Unc.
CB450 C. elegans unc-13(e450) che-3(ky1018) I. Show Description
Paralyzed Unc. This strain carries a tightly linked mutation, che-3(ky1018), that changes Q1107 of che-3 to a stop codon. Reference: Larsch, et al. (2015) Cell Reports.
CB51 C. elegans unc-13(e51) unc-122(n2916) I. Show Description
Unc. See WBPaper00003781 regarding the unc-122 mutation.
DR168 C. elegans unc-13(e51) daf-8(e1393) I. Show Description
Temperature sensitive dauer constitutive. Unc. Semi-paralyzed. Closely linked.
DR435 C. elegans dpy-5(e61) unc-13(e51) I. Show Description
Dpy. Unc.
DR478 C. elegans unc-13(e450) I; sup-7(st5) X. Show Description
sup-7 suppresses unc-13. Movement not WT. Fertility is low. Grows between 22.5C and 24C.
EU707 C. elegans air-2(or207) unc-13(e51) I. Show Description
Temperature sensitive. Grow at permissive temperature of 15C. Fully penetrant cytokinesis defect at the restrictive temperature of 25C. Semi-dominant Unc.
KR344 C. elegans let-363(h98) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Show Description
Animals with the Dup are Unc. Animals which have lost the Dup are DpyUnc and arrest in late larval development. See also WBPaper00005456.
KR345 C. elegans let-361(h97) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Show Description
Animals with the Dup are Unc. Animals which have lost the Dup are DpyUnc and arrest in late larval development.
KR350 C. elegans dpy-5(e61) let-391(h91) unc-13(e450) I; sDp2 (I;f). Show Description
Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h91 arrests as a late larva or sterile adult). Maintain by picking Unc-13 and checking for correct segregation of progeny.
KR358 C. elegans dpy-5(e61) let-355(h81) unc-13(e450) I; sDp2 (I;f). Show Description
Animals with the duplication are Unc. Animals which have lost the duplications are DpyUncLet (Sterile adults). Maintain by picking Unc non-Dpy.
KR362 C. elegans dpy-5(e61) let-388(h88) unc-13(e450) I; sDp2 (I;f). Show Description
Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h88 arrests as an early larva). Maintain by picking Unc-13 and checking for correct segregation of progeny.
KR363 C. elegans dpy-5(e61) let-387(h87) unc-13(e450) I; sDp2 (I;f). Show Description
Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h87 arrests as a mid-late larva). Maintain by picking Unc-13 and checking for correct segregation of progeny.
KR387 C. elegans unc-13(e450) rec-1(s180) I. Show Description
KR428 C. elegans inx-12(h121) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Show Description
Animals with the Dup are Unc.Animals which have lost the Dup are DpyUnc and arrest in early larval development.
KR430 C. elegans dpy-5(e61) lim-7(h110) unc-13(e450) I; sDp2 (I;f). Show Description
Animals with the Dup are Unc. Animals which have lost the Dup are DpyUnc and arrest in early larval development.
KR435 C. elegans mat-1(h104) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Show Description
Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h104 arrests as a sterile adult). Maintain by picking Unc-13 and checking for correct segregation of progeny.
KR442 C. elegans aars-2(h112) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Show Description
Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h112 arrests as a mid-stage larva). Maintain by picking Unc-13 and checking for correct segregation of progeny.
KR454 C. elegans dpy-5(e61) wdr-12(h127) unc-13(e450) I; sDp2 (I;f). Show Description
Animals with the Dup are Unc. Animals which have lost the Dup arrest as embryos to early larvae.
KR472 C. elegans unc-73(h142) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Show Description
Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest as Sterile adults.
KR621 C. elegans dpy-5(e61) cuti-1(h281) unc-13(e450) I; sDp2 (I;f). Show Description
Unc-13 phenotype. h281 arrests as an embryo. Pick Unc-13 animals to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR641 C. elegans let-506(h300) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Show Description
Animals with the Dup are Unc. Animals which have lost the Dup are DpyUncLet. Lethal->Sterile adult.
KR650 C. elegans let-518(h316) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Show Description
Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h316 arrests as an embryo or early larva). This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR717 C. elegans let-502(h392) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Show Description
Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h392 arrests as a mid-stage larva). Pick Unc-13 animals to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR727 C. elegans dpy-5(e61) let-607(h402) unc-13(e450) I; sDp2 (I;f). Show Description
Unc-13 phenotype. h402 arrests as an embryo. Pick Unc-13 animals to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR730 C. elegans let-526(h405) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Show Description
Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early/mid larval development.
MT1488 C. elegans lin-17(n677) unc-13(e1091) I. Show Description
MT3033 C. elegans unc-13(e1091) lin-35(n745) I. Show Description
Unc.
MT3184 C. elegans sem-4(n1378) unc-13(e51) I. Show Description
Unc. Egl. Transformation of sex myoblasts into body wall muscle.
MT3198 C. elegans unc-13(e1091) unc-29(e1072) I. Show Description
MT3608 C. elegans unc-13(e51) ced-1(e1735) I. Show Description
Unc. Abnormal cell death.
PJ1002 C. elegans unc-13(e51) I; ccIs55 V. Show Description
ccIs55 [unc-54::lacZ + sup-7(st5)] V. Unc.
XA4828 C. elegans unc-13(e1091) I; unc-17(e327) IV. Show Description
Previously called MA1128.