Search Strains

Pick Unc hermaphrodite to maintain (these will be tra-1/+; unc-42 him-5 dpy-21 XO animals). Segregates Unc hermaphrodites (tra-1/+ III), Unc males (+/+ III), and DpyUnc hermaphrodites (+/+ III). dpy-21 not expressed in XO. dpy-21(e428) V; XX animals are weak Dpy. dpy-21(e428) V; XO animals are non-Dpy.

Balanced well. Animals with the duplication are WT. Animals which have lost the duplication have a hermaphrodite gonad and intestine (they are self-fertile); the rest of the body is male.

Balanced well. Animals with the duplication are WT. Animals which have lost the duplication have a hermaphrodite gonad and intestine (they are self-fertile); the rest of the body is male.

Balances well. Transformer weak. Heterozygotes are WT and segregate WT, DpyUnc and males. Maintain by picking WT.

Dominant suppressor of Unc. Dpy. sup-6 is recessive lethal. Heterozygotes are Dpy non-Unc. Pick Dpy non-Unc to maintain.

Movement slow. Suppressed Unc. Revertant. Heterozygotes move slowly and segregate larval lethals (eDf1 eDp21 homozygotes), and paralyzed Uncs.

Dominant suppressor of Unc. Movement almost WT.

Suppressed Unc.

Recessive Suppressor. XO Fertile hermaphrodite. WT phenotype.

Lineage abnormal. Bursae abnormal. Segregates abnormal males. M-MATING-NO SUCCESS.

Delayed hatching from egg shell. QL and descendant cells migrate forward instead of backward (incomplete penetrance).

Abnormal cell death.

Bursae abnormal. Have slightly protruding vulva in adults. Segregates males with abnormal swollen bursae. M-MATING++ 1-10%WT.

Bursae abnormal. Vulva protruding. Segregates abnormal males. M-MATING++ 1-10%WT.

Hermaphrodites are nearly WT. Vulva slightly swollen. Males have abnormal swollen bursae. M-MATING++ 1-10%WT.

Selfed hermaphrodites produce 5% males and 2% XXX hermaphrodites (percent of viable progeny), and 30% unhatched eggs (percent of total progeny).

Temperature sensitive lethal: inviable at 25C, grows at 20C and 15C. Somewhat sickly. Small brood sizes. At 25C homozygotes have a starved translucent appearance, facilitating Nomarski visualization of neuron processes.

Homozygous viable and looks almost normal by dissecting scope, but under Nomarski microscopy the gut has a very abnormal spongy appearance, which is especially noticeable in L4 larvae.

Hermaphrodites are Dpy and Him. Males are non-Dpy and Mab. Males have abnormal bursa and defective rays. Both sexes show lateral hypodermis lineage defexts. M-MATING+POOR <1%WT.

Semidominant Unc(mild). Intragenic revertants common.

Abnormal cell death.

Long. Mechanosensory abnormal. Severe mechanosensory abnormal. Recessive.

Long. Mechanosensory abnormal.

Long. Mechanosensory Abnormal. [NOTE: originally described as carrying e1084, this strain actually carries the e75 allele. The lesion has been verified by sequence analysis. (11/26/2018)]

Long. Mechanosensory abnormal.

Long. Mechanosensory abnormal.

Dominant Mechanosensory Abnormal at 20C. Long.

Touch insensitive, lethargic.

Him. M-MATING+POOR <1%WT. Tail abnormalities->knob-like swelling in larvae and adults.

Hermaphrodites are Dpy. Males are non-Dpy and have abnormal bursae in adult, with swollen rays. Males will mate, but with very low efficiency. [3/98: King Chow isolated a line from the CGC stock that was throwing 100% Mabs. Sent the strain back to the CGC to replace the old stock.]

Hermaphrodites are Dpy and segregate males. Males are non-Dpy and Mab. Both sexes show lineage alterations.

QL migration reversed, HSN migration defective. Egl.

Extra hypodermal nuclei. DTC migration abnormal. pka lin-20.

Poorly balanced. Hets are WT and segregate WT, Dpys and ect-2 homozygotes. ect-2 homozygotes are sterile Uncs which reach adulthood, sometimes giving polynucleate oocytes. ect-2 pka let-21.

No FITC uptake by phasmids and amphids. Dauer formation defective. Osmotic avoidance defective.

Defective osmotic avoidance. FITC-.

Defective in osmotic avoidance. FITC-. Dauer defective.

Defective osmotic avoidance. FITC uptake abnormal.

Nuclei not anchored in certain epithelial cells.

Nuclei not anchored in certain epithelial cells.

Hermaphrodites are Dpy and segregates males. Males are non-Dpy and have severe tail abnormalities; frequently lethal to adult males.

Sensory neurons CEP, ADE, PDE take up FITC; tubular body of CEP cilia disrupted; slightly defective dauer formation.

Abnormal large nucleoli in all cells.

Dpy. Nuclei not anchored in certain epithelial cells.

Animals which have lost the Dup are thin, sterile, and uncoordinated. Maintain by picking WT (Egl).

e1873 allele is the only anc-1 allele in which the molecular lesion has been identified (Starr and Han, 2002) and is considered by the authors to be the reference allele. e1873 does not revert, unlike most other alleles of anc-1. Reference: Hedgecock and Thomson. Cell. 1982 Aug;30(1):321-30. Starr and Han. Science. 2002 Oct 11;298(5592):406-9.

Benomyl Resistant. Dominant at 25C--Recessive at 15C.

Heterozygotes are WT and segregate WT, Lon males and thin sterile Unc animals. Maintain by picking WT.