Strain Information
| Name | JH3553 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | meg-3(ax4503[del(1-544)::OLLAS]) meg-4(ax4504) X. |
| Description | Description: 20% maternal effect sterility on average, RNAi insensitivity, MEG-3 does not form cytoplasmic gradient. meg-3(ax4503) is an in-frame deletion in the endogenous meg-3 locus removing amino acids (1-544); MEG-3 does not form a cytoplasmic gradient but does still form granules in early embryos and co-localizes with PGL-3. References: Smith, J. et al. Elife. 2016 Dec 3;5:e21337. doi: 10.7554/eLife.21337. PMID: 27914198 Schmidt H, bioRxiv 2020.10.15.340570 (2020) doi:10.1101/2020.10.15.340570. |
| Mutagen | Crispr/Cas9 |
| Outcrossed | x0 |
| Made by | Helen Schmidt |
| Laboratory | JH |
| Reference | Schmidt, H., Putnam, A., Rasoloson, D. & Seydoux, G. Coordination of RNA and protein condensation by the P granule protein MEG-3. bioRxiv 2020.10.15.340570 (2020) doi:10.1101/2020.10.15.340570. |
Sign in
or
register an account if you want to order this strain.