Strain Information

Name BB278   View On Wormbase
Species C. elegans
Genotypeadr-1(uu49) I; rrf-3(uu56) II; adr-2(uu28) III; ggIs1 IV.
DescriptionggIs1 [nrde-3p::3xFlag::GFP::nrde-3 ORF + unc-119(+)] IV. Nuclear GFP::NRDE-3 signal. Enhanced RNAi. Lacks RNA editing. Vulval bursting. Low brood size. Triple mutants display bursting and low brood size phenotypes not observed in adr-1;adr-2 or rrf-3 parental strains. Reference: Reich DP, et al. Genes Dev. 2018 Feb 1;32(3-4):271-282.
MutagenNo mutagen
Made byDaniel Reich
Laboratory BB
Reference Reich DP, Tyc KM, and Bass BL (2018). C. elegans ADARs antagonize silencing of cellular dsRNAs by the antiviral RNAi pathway. Genes Dev 32, 271-282.
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