Strain Information

Name UP2815   View On Wormbase
Species C. elegans
GenotypecsSi2 [lin-3::lin-3XL + unc-119(+)] II; lin-3(n1059) IV/nT1[qIs51] (IV;V)
Descriptionlin-3(-) heterozygous balanced strain containing single copy MOS-mediated insertion of csSi1 transgene encoding lin-3XL (extra long) splice isoform, expressed under control of the lin-3 promoter. The transgene partially rescues lethality (but not Vulvaless or sterile phenotypes) of lin-3 mutants, which can be recognized by absence of myo-2::GFP from the nT1 balancer. Pick GFP+ to maintain.
MutagenNo mutagen
Outcrossedx2
Made byPu Pu
Laboratory UP
Reference Pu, P., Stone, C.E., Burdick, J.T., Murray, J.I. and Sundaram, M.V. (2017). The lipocalin LPR-1 cooperates with LIN-3/EGF signaling to maintain narrow tube integrity in Caenorhabditis elegans. Genetics 205, 1247-1260. PMCID: PMC5340336
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