Gene Information: lin-3

Namelin-3 View on WormBase
Species C. elegans
SequenceF36H1.4
Genetic positionIV:4.82 +/- 0.005 cM
Genomic positionIV: 11054308..11063768

Strains carrying this gene

Strain Genotype Description
CB1417 lin-3(e1417) IV. Vulvaless. Recessive. M-MATING+++ 10-30%WT.
MT1348 dpy-20(e1362) lin-3(e1417) IV. Dpy. Vul.
MT2136 lin-3(n1058)/unc-8(e49) dpy-20(e1362) IV. Heterozygotes are WT and segregate WT, DpyUnc and Steriles (n1058 homozygotes). The n1058 homozygous larvae are occasionally paralyzed. Maintain by picking WT.
MT378 lin-3(n378) IV. Vulvaless. Isolated in lin-8(n111); this strain may still contain n111.
MT4684 lin-3(n1059) dpy-20(e1362)/unc-24(e138) mec-3(e1338) dpy-20(e1282) IV. Heterozygotes are Dpy and segregate Dpy, Dpy Lethals (early larval) and DpyUncMec.
PJ1166 daf-2(m41) III; ccIs55 V; njEx38. ccIs55 [unc-54::lacZ + sup-7(st5)] V. njEx38 [unc-54p::daf-2(+) + goa-1p::GFP + rol-6(su1006)]. Maintain by picking Rollers. Arrest as dauers at 25C. Maintain at 15C.
PS1378 itr-1(sy290) lin-3(n1058) IV. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
PS1595 lfe-2(sy326) I; lin-3(n1058) dpy-20(e1282) IV. sy326 suppresses the sterility of n1058. Dpy. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
UP2813 csSi3 [lin-3::lin-3S + unc-119(+)] II; lin-3(n1059) IV/nT1[qIs51] (IV;V) lin-3(-) heterozygous balanced strain containing single copy MOS-mediated insertion of csSi1 transgene encoding lin-3S (short) splice isoform, expressed under control of the lin-3 promoter. The transgene rescues lethal and Vulvaless phenotypes (but not sterility) of lin-3 mutants, which can be recognized by absence of myo-2::GFP from the nT1 balancer. Pick GFP+ to maintain.
UP2814 csSi1 [lin-3::lin-3L + unc-119(+)] II; lin-3(n1059) IV/nT1[qIs51] (IV;V) lin-3(-) heterozygous balanced strain containing single copy MOS-mediated insertion of csSi1 transgene encoding lin-3L (long) splice isoform, expressed under control of the lin-3 promoter. The transgene partially rescues lethal and Vulvaless phenotypes (but not sterility) of lin-3 mutants, which can be recognized by absence of myo-2::GFP from the nT1 balancer. Pick GFP+ to maintain.
UP2815 csSi2 [lin-3::lin-3XL + unc-119(+)] II; lin-3(n1059) IV/nT1[qIs51] (IV;V) lin-3(-) heterozygous balanced strain containing single copy MOS-mediated insertion of csSi1 transgene encoding lin-3XL (extra long) splice isoform, expressed under control of the lin-3 promoter. The transgene partially rescues lethality (but not Vulvaless or sterile phenotypes) of lin-3 mutants, which can be recognized by absence of myo-2::GFP from the nT1 balancer. Pick GFP+ to maintain.
VT723 lin-28(n719) I; lin-3(e1417) IV. Egl. Vulvaless due to lin-3. Precocious VPC divisions and adult alae due to lin-28.