Strain Information
| Name | PHX2171 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | set-2(syb2085)/qC1 [dpy-19(e1259) glp-1(q339) qIs26] III. |
| Description | Maintain at 20C or cooler. qIs26 [lag-2::GFP + rol-6(su1006)]. set-2 mutation balanced by glp-1- and dpy-19-marked recombination suppressor. qIs26 was integrated into qC1 and in the process made qC1 homozygous lethal. Heterozygotes are Rollers and GFP+ in the distal tip cell, and segregate WT Rol, lethal qC1 homozygotes, and set-2(syb2085) homozygotes (Mrt phenotype at 25C -- viable but homozygotes will become sterile in successive generations). Pick WT GFP+ Rol and check for correct segregation of progeny to maintain. set-2(syb2085) mutant animals that express a catalytically inactive form of SET-2, the C. elegans SET1 homolog. set-2(syb2085) homozygotes are not long-lived on OP50. Reference: Caron M, et al. Life Sci Alliance. Dec 2021, 5 (3) e202101140; DOI: 10.26508/lsa.202101140. PMID: 34893559. |
| Mutagen | No mutagen |
| Outcrossed | x2 |
| Made by | Cécile Bedet & Suny Biotech |
| Laboratory | PFR |
| Reference | Caron et al 2021 Life Sci Alliance doi: 10.26508/lsa.202101140. |
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