Strain Information
| Name | JK6432 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | mpk-1(q1190)/qC1 [dpy-19(e1259) glp-1(q339) qIs26] III. |
| Description | Heterozygous animals Roll and have GFP(+) distal tip cells. Segregates roller GFP(+) heterozygotes and non-roller GFP(-) mpk-1 homozygotes which are sterile and vulvaless. qC1 [dpy-19(e1259) glp-1(q339) qIs26] homozygotes are not viable. q1190 is a deletion in mpk-1 that removes 2221bp between axons 2-7 (based on mpk-1b annotation). Sequence is shared between mpk-1a and mpk-1b. The deletion is in frame and leaves 27bp of coding sequence.Reference: Robinson-Thiewes S, et al. Cell Rep. 2021 May 25;35(8):109162. doi: 10.1016/j.celrep.2021.109162. |
| Mutagen | Crispr/Cas9 |
| Outcrossed | x2 |
| Made by | Sarah Robinson-Thiewes |
| Laboratory | JK |
| Reference | Non-autonomous regulation of germline stem cell proliferation by somatic MPK-1/MAPK activity in C. elegans Robinson-Thiewes et al., Cell Reports, Vol.35, Issue 8, May 25,2021 https://doi.org/10.1016/j.celrep.2021.109162 |
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