Strain Information
| Name | YA1116 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | mrt-1(tm1354) I. |
| Description | Null allele. Mortal germline. Progressive telomere shortening due to telomerase dysfunction. Hypersensitive to DNA interstrand crosslinking agents. This strain will become sterile after propagating 10-20 generations. mrt-1 mutants can be rejuvenated by outcrossing. Reference: Meier B, et al. EMBO J. 2009 Nov 18;28(22):3549-63. |
| Mutagen | |
| Outcrossed | x12 |
| Made by | Shawn Ahmed |
| Laboratory | YA |
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