Strain Information

Name XE1158   View On Wormbase
Species C. elegans
GenotypejuIs76 II; wpIs15 X.
DescriptionjuIs76 [unc-25p::GFP + lin-15(+)] II. GFP expression in GABAergic motor neurons. wpIs15 [unc-47p::KillerRed] X. Slight Unc. KillerRed is a red fluorescent protein and photosensitizer that efficiently generates reactive oxygen species (ROS) when activated by light. wpIs15 produces a Shrinker phenotype after illumination by white light for 2 hrs. Reference: Williams DC, et al. Cell Rep. 2013 Oct 31;5(2):553-63.
MutagenNo mutagen
Outcrossedx0
Made byDan Williams
Laboratory XE
Reference Williams DC, Bejjani RE, Ramirez PM, Coakley S, Kim SA, Lee H, Wen Q, Samuel A,Lu H, Hilliard MA, Hammarlund M. Rapid and permanent neuronal inactivation invivo via subcellular generation of reactive oxygen with the use of KillerRed.Cell reports. 2013; 5(2):553-63. NIHMSID: NIHMS527725 PubMed [journal] PMID:24209746, PMCID: PMC3877846
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