Strain Information
| Name | WIN253 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | glh-4(jog16) glh-2(jog49) glh-1(jog50) I. |
| Description | Temperature sensitive: maintain at 15-20C. Reduced number of progeny and mortal germline phenotype at elevated temperatures. Engineered mutations of FG repeats in three Vasa like GLH proteins (GLH-1, GLH-2 and GLH-4). glh-1(jog50) is F to A substitution. glh-4(jog16) is F to A substitution. glh-2(jog49) is a deletion of the FG repeats. This strain exhibits a subtle change in germ granule composition while maintaining their architecture. WAGO-4 is mislocalized to the cytoplasm leading to compromised function. |
| Mutagen | No mutagen |
| Outcrossed | x1 |
| Made by | Joseph Gokcezade, Peter Duchek |
| Laboratory | WIN |
| Reference | Jelenic et al - In revision |
Sign in
or
register an account if you want to order this strain.