Strain Information
| Name | PHX9026 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | lat-1(syb9026[lat-1(delta Lec)] *syb8408) II. |
| Description | CRISPR/Cas9-engineered deletion of Lectin domain within endogenously-tagged LAT-1A. Internal eGFP and FLAG tags with poly-A linkers inserted into endogenous lat-1 locus before 651 aa. Reduced brood size and high levels of embryonic and larval lethality. Reference: Carmona-Rosas G, et al. bioRxiv 2023.05.04.539414; doi: https://doi.org/10.1101/2023.05.04.539414. |
| Mutagen | Crispr/Cas9 |
| Outcrossed | x0 |
| Made by | SunyBiotech |
| Laboratory | KRA |
| Reference | Carmona-Rosas, Li, Smith et al. "Structural basis and functional roles for Toll-like receptor binding to Latrophilin adhesion-GPCR in embryo development." bioRxiv (2023) doi: https://doi.org/10.1101/2023.05.04.539414 |
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