Strain Information
| Name | PHX5866 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | flp-11(syb5866) X. |
| Description | Molecular null allele. syb5866 is a CRISPR-engineered deletion of the entire flp-11 coding region. Strongly reduces sleep. Reference: Rossi L, et al. Curr Biol. 2025 Apr 20:S0960-9822(25)00355-0. doi: 10.1016/j.cub.2025.03.039. PMID: 40273913. |
| Mutagen | Crispr/Cas9 |
| Outcrossed | x0 |
| Made by | SunyBiotech / Henrik Bringmann |
| Laboratory | HBR |
| Reference | “The neuropeptide FLP-11 induces and self-inhibits sleep through the receptor DMSR-1 in Caenorhabiditis elegans” doi: 10.1016/j.cub.2025.03.039. |
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