Strain Information
| Name | PHX2172 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | sin-3(syb2172) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III). |
| Description | Maternal effect sterile deletion balanced by bli-4- and GFP-marked translocation. Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP+, arrested hT2 aneuploids, and non-GFP syb2172 homozygotes (maternal effect sterile). Homozygous hT2[bli-4 let-? qIs48] inviable. Pick WT GFP+ and check for correct segregation of progeny to maintain. syb2172 is CRISPR-engineered deletion removing the ATG start codon and entire sin-3 coding region. Reference: Robert VJ, et al. Development. 2023 Oct 17;150(21):dev201755. doi: 10.1242/dev.201755 PMID: 37818613. |
| Mutagen | CRISPR-Cas9 |
| Outcrossed | x0 |
| Made by | Suny Biotech |
| Laboratory | PFR |
| Reference | Robert VJ et al. Development 2023 doi: 10.1242/dev.201755. |
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