Strain Information
| Name | KX110 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | ced-9(n1653) mab-5(mu14) III; bcIs39 V. |
| Description | bcIs39 [lim-7p::ced-1::GFP and lin-15(+)] V. Temperature sensitive induction of germ cell apoptosis at 25 C. Large number of germ cells are decorated by CED-1::GFP within 48 h. Activates CED-3-mediated cleavage of IFG-1, visualized by western blot (Contreras, V., et al, 2011). |
| Mutagen | none |
| Outcrossed | x1 |
| Made by | Andrew J Friday |
| Laboratory | KX |
| Reference | 1. Contreras, V., Friday, A.J., Morrison, J.K., Hao, E., and Keiper, B.D. (2011). Cap-Independent translation promotes C. elegans germ cell apoptosis through Apaf-1/CED-4 in a caspase-dependent mechanism. PLoS ONE 6, e24,444. 2. Morrison, J.K., Friday, A.J., Henderson, M.A., Hao, E., and Keiper, B.D. (2014). Induction of cap-independent BiP (hsp-3) and Bcl-2 (ced-9) translation in response to eIF4G (IFG-1) depletion in C. elegans. Translation 2, e28935. |
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