Strain Information

Name KX110   View On Wormbase
Species C. elegans
Genotypeced-9(n1653) mab-5(mu14) III; bcIs39 V.
DescriptionbcIs39 [lim-7p::ced-1::GFP and lin-15(+)] V.  Temperature sensitive induction of germ cell apoptosis at 25 C. Large number of germ cells are decorated by CED-1::GFP within 48 h. Activates CED-3-mediated cleavage of IFG-1, visualized by western blot (Contreras, V., et al, 2011).
Made byAndrew J Friday
Laboratory KX
Reference 1. Contreras, V., Friday, A.J., Morrison, J.K., Hao, E., and Keiper, B.D. (2011). Cap-Independent translation promotes C. elegans germ cell apoptosis through Apaf-1/CED-4 in a caspase-dependent mechanism. PLoS ONE 6, e24,444. 2. Morrison, J.K., Friday, A.J., Henderson, M.A., Hao, E., and Keiper, B.D. (2014). Induction of cap-independent BiP (hsp-3) and Bcl-2 (ced-9) translation in response to eIF4G (IFG-1) depletion in C. elegans. Translation 2, e28935.
Sign in or register an account if you want to order this strain.