Strain Information

Name JK5796   View On Wormbase
Species C. elegans
Genotypelst-1(q869) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III).
DescriptionHeterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested hT2 aneuploids, and non-GFP q869 homozygotes (viable and somewhat fertile). Homozygous hT2[bli-4 let-? qIs48] inviable. Pick WT GFP and check for correct segregation of progeny to maintain. q869 is a deletion of the entire lst-1 coding sequence as well as 139 bp upstream of M71 start codon and 228 bp downstream of the coding sequence. Reference: Haupt KA, et al. Development. 2019 Oct 17;146(20):dev181644. doi: 10.1242/dev.181644. PMID: 31515205
Made byKim Haupt
Laboratory JK
Reference Haupt KA, Enright AL, Ferdous AS, Kershner A, Shin H, Wickens M, and Kimble J. (2019) The molecular basis of LST-1 self-renewal activity and its control of stem cell pool size. Development, 146(20). [PDF] [PubMed]
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