Strain Information
| Name | HA2846 View On Wormbase |
|---|---|
| Species | C.elegans |
| Genotype | fust-1(rt256[R446S]) II. |
| Description | fust-1(rt256[R446S]) was created by CRISPR editing of arginine codon in C. elegans fust-1 to create FUS disease model for human mutation R524S. This strain also contains additional silent edits (also present in control strain HA2845), and was back-crossed to remove the pha-1 allele used in strain construction. Under normal culture conditions HA2846 animals are superficially wild-type; after stress latent defects are observed. Reference: Baskoylu S, et al. bioRxiv 799932; doi: https://doi.org/10.1101/799932 |
| Mutagen | No mutagen |
| Outcrossed | x4 |
| Made by | Saba Baskoylu |
| Laboratory | HA |
| Reference | bioRxiv 799932; doi: https://doi.org/10.1101/799932 |
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