Strain Information
| Name | ESC440 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | reSi2 II; tsr-2(cse424[tsr-2::degron::GFP]) IV. |
| Description | Maintain at 15-20C. reSi2 [col-10p::TIR1::F2A::mTagBFP2::AID*::NLS::tbb-2 3'UTR] (II:0.77). Hypodermal-specific expression of TIR1 co-factor for AID. degron::GFP tag inserted into the C-terminus of endogenous tsr-2 locus. This strain can be used for auxin-inducible degradation (AID) of TSR-2 in epidermal tissues. Nucleolar GFP expression. Reference: Zhao Q., et al. PLoS Biol. 2023 Aug 31;21(8):e3002276. doi: 10.1371/journal.pbio.3002276. PMID: 37651423. |
| Mutagen | Crispr/Cas9, crossing |
| Outcrossed | x2 |
| Made by | Qiuxia Zhao |
| Laboratory | ESC |
| Reference | Zhao, Q., Rangan, R., Weng, S., Ozdemir, C. , Cenik, E. S. Inhibition of ribosome biogenesis in the epidermis is sufficient to trigger organism-wide growth quiescence independently of nutritional status in C. elegans (2023). PLOS Biology, https://doi.org/10.1371/journal.pbio.3002276 |
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