Strain Information

Name DCR4750   View On Wormbase
Species C. elegans
GenotypeolaIs35 X.
DescriptionolaIs35 [ttx-3Gp::eGFP::lgg-1 + ttx-3Gp::mCherry + unc-122p::RFP]. Integrated transgene allows visualization of autophagosomes in a single neuron (AIY). "ttx-3G" refers to genomic fragment containing AIY motif described in Bertrand & Hobert Dev Cell. 2009 Apr;16(4):563-75. References: Stavoe AK, et al. Dev Cell. 2016 Jul 25;38(2):171-85. Hill SE, et al. Dev Cell. 2019 Mar 8. pii: S1534-5807(19)30104-2.
Made bySarah Hill
Laboratory DCR
Reference Stavoe, AK, Hill, SE, Hall, DH, Colón-Ramos, DA (2016). “KIF1A/UNC-104 Transports ATG-9 to Regulate Neurodevelopment and Autophagy at Synapses.” Dev. Cell.25;38(2):171-85. Hill, SE, Kauffman, K, Krout, M, Richmond JE, Melia, T, Colón-Ramos, DA (2019). “Maturation and Clearance of Autophagosomes in Neurons Depends on a Specific Cysteine Protease Isoform, ATG-4.2.” Developmental Cell,
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