Strain Information
Name | CA1117 View On Wormbase |
---|---|
Species | C. elegans |
Genotype | dsb-1(we11) IV/nT1[unc-?(n754) let-?] (IV;V). |
Description | Heterozygotes are Unc and segregate Uncs, dead eggs, and non-Uncs (dsb-1 homozygotes), which produce 99% inviable embryos due to meiotic nondisjunction. Pick Unc to maintain and check for correct segregation of progeny. we11 is a TCA to TAA nonsense mutation in the dsb-1 coding sequence that introduces a premature stop after leucine 96. Reference: Stamper EL, et al. PLoS Genet. 2013;9(8):e1003679. |
Mutagen | No mutagen |
Made by | Ericca Stamper |
Laboratory | CA |
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