Strain Information

Name CA1117   View On Wormbase
Species C. elegans
Genotypedsb-1(we11) IV/nT1[unc-?(n754) let-?] (IV;V).
DescriptionHeterozygotes are Unc and segregate Uncs, dead eggs, and non-Uncs (dsb-1 homozygotes), which produce 99% inviable embryos due to meiotic nondisjunction. Pick Unc to maintain and check for correct segregation of progeny. we11 is a TCA to TAA nonsense mutation in the dsb-1 coding sequence that introduces a premature stop after leucine 96. Reference: Stamper EL, et al. PLoS Genet. 2013;9(8):e1003679.
MutagenNo mutagen
Made byEricca Stamper
Laboratory CA
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