Strain Information
| Name | BU7222 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | pat-3(st564) III; kqEx73. |
| Description | kqEx73 [pat-3(sp) + rab-3::RFP + cki-1::GFP]. Pick RFP+ to maintain. kqEx73 carries a form of pat-3 gene with splicing defects; rescues pat-3 null allele. pat-3(sp) is a frameshift mutation in the splice acceptor region (ag to aa) that abolishes conserved interaction domains such as the NPxY motifs and creates a splice variant with an extra 19 amino acids. The pat-3(sp) animals not only produce mutant pat-3, but also express the regular splice form due to utilization of an unusual splice acceptor. Abnormal Distal Tip Cell migration and pat-3 gene splicing (intron 7) defects. Reference: Kihira S, et al. PLoS One. 2012;7(8):e42425. |
| Mutagen | none |
| Outcrossed | x0 |
| Made by | Shingo Kihira |
| Laboratory | BU |
| Reference | PLoS One. 2012;7(8):e42425. |
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