| EU149 |
C. elegans |
mex-3(or20)/hT1 I; +/hT1 V; lin-2(e1309) X. Show Description
Strain is egg-laying defective. Homozygous mex-3(or20) is a non-conditional maternal effect lethal: worms fill up with dead eggs. Heterozygotes bag with 11/16 dead embryos and larvae. About 10% of worms can lay eggs and be mated into for outcrossing. The mex-3(or20) mutant embryos produce excess body wall muscle anteriorly.
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| EU1472 |
C. elegans |
let-99(or204) IV; him-5(e1490) V. Show Description
let-99(or204) is temperature-sensitive, maternal-effect, embryonic-lethal. Nearly completely penetrance of lethality at 26C. Viable at 15C. Maintain at 15C. Reference: Goulding MB, et al. J Cell Biol. 2007 Sep 24;178(7):1177-91.
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| EU3501 |
C elegans |
apx-1(or2015) V/nT1 [unc-?(n754) let-?] (IV;V). Show Description
Heterozygous. Pick Unc to maintain. Heterozygotes are Unc and segregate Unc heterozygotes, wildtype (or2015 homozygotes that give only dead progeny), and and arrested nT1 aneuploids. Pick Unc and check for correct segregation of progeny to maintain. or2015 is a CRISPR/Cas9-engineered null allele removing the entire apx-1 open reading frame. Reference: Chuang CH, et al. G3 (Bethesda). 2025 Sep 26:jkaf229. doi: 10.1093/g3journal/jkaf229. PMID: 41004705.
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| EU630 |
C. elegans |
air-2(or207) I. Show Description
Temperature sensitive. Grow at permissive temperature of 15C. Fully penetrant cytokinesis defect at the restrictive temperature of 25C.
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| EU640 |
C. elegans |
cul-2(or209) III. Show Description
Temperature sensitive. Maintain at 15C.
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| EU641 |
C. elegans |
cul-2(or209) III; him-8(e1489) IV. Show Description
Temperature sensitive. Maintain at 15C.
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| EU707 |
C. elegans |
air-2(or207) unc-13(e51) I. Show Description
Temperature sensitive. Grow at permissive temperature of 15C. Fully penetrant cytokinesis defect at the restrictive temperature of 25C. Semi-dominant Unc.
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