Strain Information

Name ZM9062   View On Wormbase
Species C. elegans
GenotypehpIs583.
DescriptionhpIs583 [acr-2(s)p::tomm20::miniSOG::SL2::RFP]. Maintain in the covered box to avoid unnecessary exposure to ambient light. Stimulation with blue light (460 nm LED light for 30 min at 4 Hz with 2 mW/mm2), induces mitochondrial-miniSOG ablation of A- and B-class motor neurons. During neuron ablation, it is recommended to keep the lid of the plate open and use a heat disipator to keep the air cool. acr-2s(p) is a 1.8 kb fragment of the acr-2 promoter driving expression in only A- and B- class motor neurons (described in Jospin et al, 2009 PLoS Biol. Dec;7(12):e1000265). Generated in N2 background. Reference: Gao S, et al. eLife 2018 Jan 23;7:e29915. doi: 10.7554/eLife.29915.
MutagenUV Rays
Outcrossedx4
Made byMei Zhen
Laboratory ZM
Reference Gao, S. et al. Excitatory motor neurons are local oscillators for backward locomotion. Elife7, e29915 (2018).
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