Strain Information
| Name | ZM5398 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | hpIs199. |
| Description | hpIs199 [myo-3p::ChR2::GFP + lin-15(+)]. Muscle specific channelrhodopsin strain. Weak GFP in muscles. [NOTE: (06/24/2025) The transgene in this strain was previously incorrectly described as myo-3p::GCaMP6::mCherry + lin-15(+). The correct transgene is hpIs199 [myo-3p::ChR2::GFP + lin-15(+)]. References: Meng J, et al. Sci Adv. 2024 Apr 12;10(15):eadk0002. doi: 10.1126/sciadv.adk0002. PMID: 38598630. Lu Y, et al. Curr Biol. 2022 Nov 7;32(21):4631-4644.e5. doi: 10.1016/j.cub.2022.09.002. PMID: 36182701. |
| Mutagen | |
| Outcrossed | x4 |
| Made by | Mei Zhen |
| Laboratory | ZM |
| Reference | Meng J, Ahamed T, Yu B, Hung W, El Mouridi S, Leclercq-Blondel A, Gendrel M, Wang Z, Chen L, Wen Q, Boulin T, Gao S, Zhen M. A tonically active master neuron continuously modulates mutually exclusive motor states at two-time scales. Science Advances 10(15):eadk0002. |
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