Strain Information
| Name | ZM10113 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | twk-40(bln282[twk-40::TagRFP::ZF1]) III; hpIs727. |
| Description | hpIs727 [rig-3p::zif-1::sl2::RFP + ttx-3p::GFP]. twk-40(bln282) is a CRISPR generated allele of the endogenous twk-40 locus, inserting TagRFP and ZF1 allowing visualization of endogenous protein expression and localization as well as ZIF-1-mediated degradation. hpIs727 provides AVA neuron-specific expression of ZIF-1, leading to depletion of TWK-40 from AVA. Animals have loopy forward and reversal movements compared to twk-40(bln282) alone. |
| Mutagen | |
| Outcrossed | x0 |
| Made by | Jun Meng |
| Laboratory | ZM |
| Reference | A tonically active neuron continuously drives mutually exclusive motor states at different timescales. Meng et al., 2023. Submitted. |
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