Strain Information
| Name | XE2260 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | casy-1(wp78) II. |
| Description | wp78 is a CRISPR/Cas9-engineered 11.5 kb deletion removing the entire coding region of casy-1, the C. elegans homolog of calsyntenin. casy-1(wp78) phenocopies the casy-1(wp60) point mutation and strongly suppresses PVQ degeneration in both ric-7(n2657) and miro-1(wy50180); mtx-2(wy50266) mutants. Reference: Ding C, et al. Elife. 2022 Mar 14;11:e73557. PMID: 35285800. |
| Mutagen | Crispr/Cas9 |
| Outcrossed | x0 |
| Made by | Chen Ding |
| Laboratory | XE |
| Reference | Ding C, Wu Y, Dabas H, Hammarlund M. Activation of the CaMKII-Sarm1-ASK1-p38 MAP kinase pathway protects against axon degeneration caused by loss of mitochondria. Elife. 2022 Mar 14;11:e73557. doi: 10.7554/eLife.73557. PMID: 35285800; PMCID: PMC8920508. |
Sign in
or
register an account if you want to order this strain.