Strain Information

Name XE1220   View On Wormbase
Species C elegans
GenotypewpEx76.
DescriptionwpEx76 [myo-3p::tom20::tdKillerRed + unc-122p::GFP]. Pick GFP+ to maintain. KillerRed is a red fluorescent protein and photosensitizer that efficiently generates reactive oxygen species (ROS) when activated by light. wpEx76 carries a tandem dimer version of KillerRed targeted to the mitochondria by the addition of a tom-20 targeting sequence (mito-tdKillerRed). Reference: Williams DC, et al. Cell Rep. 2013 Oct 31;5(2):553-63.
MutagenNo mutagen
Outcrossedx0
Made byDan Williams
Laboratory XE
Reference Williams DC, Bejjani RE, Ramirez PM, Coakley S, Kim SA, Lee H, Wen Q, Samuel A, Lu H, Hilliard MA, Hammarlund M. Rapid and permanent neuronal inactivation in vivo via subcellular generation of reactive oxygen with the use of KillerRed. Cell reports. 2013; 5(2):553-63. NIHMSID: NIHMS527725 PubMed [journal] PMID: 24209746, PMCID: PMC3877846
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