Strain Information
| Name | WRM113 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | mex-3(spr37) I. |
| Description | Homozygous fertile, reduced brood at 25C. mex-3(spr37) is a CRISPR/Cas9 engineered indel removing nucleotides 28-651 of the mex-3 3’ UTR and inserting the sequence 5’-TTCATTCCAATT-3’ between break points. Displays temperature-sensitive embryonic lethality phenotype at 25C seen in other mex-3 3’ UTR deletion strains, though less penetrate than observed in GFP-tagged mutants. Derived in N2 background. Reference: Brown HE, et al. Development. 2025 Sep 1;152(17):dev204740. doi: 10.1242/dev.204740. PMID: 40787769. |
| Mutagen | No mutagen |
| Outcrossed | x3 |
| Made by | Hannah Brown |
| Laboratory | WRM |
| Reference | Brown HE, et al. Development. 2025 Sep 1;152(17):dev204740. doi: 10.1242/dev.204740. PMID: 40787769. |
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