Strain Information

Name WG300   View On Wormbase
Species C.elegans
GenotypermIs190; hdEx2.
DescriptionrmIs190 [F25B3.3p::Q67::CFP]. hdEx2 [snb-1::ALKBH3(H257A)::BFP::tbb-2 3’UTR + rol-6(su1006)]. Pick Rollers to maintain. BFP fused to the C-terminus of catalytically inactive ALKBH3(H257A) mutant form of ALKBH3. Pan-neuronal CFP expression. Reference: Sun Y, et al. Nature. 2023 Nov;623(7987):580-587. doi: 10.1038/s41586-023-06701-5. PMID: 37938769.
MutagenNo mutagen
Made byHui Dai
Laboratory 4010
Reference Sun, Y., Dai, H., Dai, X. et al. m1A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration. Nature 623, 580–587 (2023).
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