Strain Information

Name UP3542   View On Wormbase
Species C. elegans
Genotypelpr-3(cs231) X; csEx436.
DescriptioncsEx436 [lpr-3 (fosmid WRM619dE09) + myo-2p::mCherry]. Pick mCherry+ animals to maintain. cs231 is a Crispr/Cas9-induced null allele of lpr-3: a 13 nucleotide deletion in exon 1 results in frameshift. Homozygous mutants are embryonic lethal, but are rescued by csEx436 containing lpr-3(+) fosmid WRM619dE09. NOTE: lpr-3(cs231) should be considered the canonical allele as ok2351 also perturbs expression of adjacent gene lpr-6. Reference: Forman-Rubinsky R, Cohen JD and Sundaram MV. Genetics. 2017 Oct;207(2):625-642.
Made byRachel Forman-Rubinsky
Laboratory UP
Reference Forman-Rubinsky, R., Cohen, J.D. and Sundaram, M.V. (2017). Lipocalins are required for apical extracellular matrix organization and remodeling in Caenorhabditis elegans. Genetics 207, 625-642.
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