Strain Information
| Name | TG4300 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | lem-3(gt3311[eGFP::Stag::lem-3[Y556A G558A]]) I. |
| Description | Endogenous lem-3 locus carries GFP tag and two misense mutations in conserved residues [Y556A G558A] of GIY-YIG nuclease domain. Homozygous viable, though [Y556A G558A] mutants exhibit increased embryonic lethality after irradiation and abolished localization of GFP::LEM-3 at the midbodies. Reference: Hong Y, et al. Nat Commun. 2018 Feb 20;9(1):728. |
| Mutagen | |
| Outcrossed | x6 |
| Made by | Ye Hong |
| Laboratory | TG |
| Reference | Nat Commun. 2018 Feb 20;9(1):728. |
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