Strain Information

Name TG4300   View On Wormbase
Species C. elegans
Genotypelem-3(gt3311[eGFP::Stag::lem-3[Y556A G558A]]) I.
DescriptionEndogenous lem-3 locus carries GFP tag and two misense mutations in conserved residues [Y556A G558A] of GIY-YIG nuclease domain. Homozygous viable, though [Y556A G558A] mutants exhibit increased embryonic lethality after irradiation and abolished localization of GFP::LEM-3 at the midbodies. Reference: Hong Y, et al. Nat Commun. 2018 Feb 20;9(1):728.
Made byYe Hong
Laboratory TG
Reference Nat Commun. 2018 Feb 20;9(1):728.
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