Strain Information

Name SZ299   View On Wormbase
Species C. elegans
Genotypeunc-73(e936) I; prp-8(az117) III.
Descriptionprp-8(az117) is a CRISPR-engineered R540K missense allele that suppress unc-73(e936) uncoordination through activation of an in-frame cryptic 5'ss. Reference: Cartwright-Acar CH, et al. Nucleic Acids Res. 2022 Nov 11;50(20):11834-11857. doi: 10.1093/nar/gkac991. PMID: 36321655.
Made byAlan Zahler
Laboratory SZ
Reference Catiana H Cartwright-Acar and others, A forward genetic screen in C. elegans identifies conserved residues of spliceosomal proteins PRP8 and SNRNP200/BRR2 with a role in maintaining 5′ splice site identity, Nucleic Acids Research, Volume 50, Issue 20, 11 November 2022, Pages 11834–11857,
Sign in or register an account if you want to order this strain.