Strain Information
| Name | SZ299 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | unc-73(e936) I; prp-8(az117) III. |
| Description | prp-8(az117) is a CRISPR-engineered R540K missense allele that suppress unc-73(e936) uncoordination through activation of an in-frame cryptic 5'ss. Reference: Cartwright-Acar CH, et al. Nucleic Acids Res. 2022 Nov 11;50(20):11834-11857. doi: 10.1093/nar/gkac991. PMID: 36321655. |
| Mutagen | Crispr/Cas9 |
| Outcrossed | x2 |
| Made by | Alan Zahler |
| Laboratory | SZ |
| Reference | Catiana H Cartwright-Acar and others, A forward genetic screen in C. elegans identifies conserved residues of spliceosomal proteins PRP8 and SNRNP200/BRR2 with a role in maintaining 5′ splice site identity, Nucleic Acids Research, Volume 50, Issue 20, 11 November 2022, Pages 11834–11857, https://doi.org/10.1093/nar/gkac991 |
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