Strain Information

Name SZ155   View On Wormbase
Species C. elegans
Genotypeunc-73(e936) I; prp-8(az29) III.
Descriptionprp-8(az29) is a G654E missense mutation. az29 is a CRISPR-induced mutation mimicking a known suppressor of unc-73(e936). It changes cryptic splicing of e936 to allow for an increase in full-length unc-73 expression. Reference: Mayerle M, et al. Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2193-2199. doi: 10.1073/pnas.1819020116. PMID: 30674666.
Made byAlan Zahler
Laboratory SZ
Reference Mayerle M, Yitiz S, Soulette C, Rogel LE, Ramirez A, Ragle JM, et al. Prp8 impacts cryptic but not alter- native splicing frequency. Proc Natl Acad Sci U S A. 2019; 116: 2193–2199. pnas.1819020116 PMID: 30674666 Sequence of the az29 allele is described in methods for this paper
Sign in or register an account if you want to order this strain.