Strain Information
| Name | SX3073 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | mjIs588 II; unc-119(ed3) III |
| Description | mjIs588 [mex-5p::GFP::his-58::21UR-1target::tbb-2 3'UTR + unc-119(+)] II. mjIs588 was derived by removing introns 2 and 3 from the construct used to generate the mjIs144 transgene. Single copy inserted into ttTi5605 (MosSCI). Superficially wild-type. mjIs588 GFP is silenced in wild-type animals and de-silenced in hrde-1 mutant animals. Reference: Akay A, et al. Dev Cell. 2017 Aug 7;42(3):241-255.e6. |
| Mutagen | No mutagen |
| Outcrossed | x0 |
| Made by | Alper Akay |
| Laboratory | SX |
| Reference | Akay, Alper, Tomas Di Domenico, Kin M. Suen, Amena Nabih, Guillermo E. Parada, Mark Larance, Ragini Medhi, et al. 2017. “The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription.” Developmental Cell 42 (3): 241–55.e6. |
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