Strain Information

Name SX3073   View On Wormbase
Species C. elegans
GenotypemjIs588 II; unc-119(ed3) III
DescriptionmjIs588 [mex-5p::GFP::his-58::21UR-1target::tbb-2 3'UTR + unc-119(+)] II. mjIs588 was derived by removing introns 2 and 3 from the construct used to generate the mjIs144 transgene. Single copy inserted into ttTi5605 (MosSCI). Superficially wild-type. mjIs588 GFP is silenced in wild-type animals and de-silenced in hrde-1 mutant animals. Reference: Akay A, et al. Dev Cell. 2017 Aug 7;42(3):241-255.e6.
MutagenNo mutagen
Made byAlper Akay
Laboratory SX
Reference Akay, Alper, Tomas Di Domenico, Kin M. Suen, Amena Nabih, Guillermo E. Parada, Mark Larance, Ragini Medhi, et al. 2017. “The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription.” Developmental Cell 42 (3): 241–55.e6.
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