Strain Information
| Name | QC154 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | paqr-2(tm3410) III; paqr-1(tm3262) IV. |
| Description | This double mutant strain has a severely deformed tail tip and is intolerant of cold (will not grow then die at 15°C) and of dietary saturated fatty acids. Its cell membranes are rigid and rich in saturated fatty acids, and the strain has a small brood size, slow locomotion, permeable cells, autophagy defects as well as other phenotypes. References: Svensson E, et al. PLoS ONE 6(6):e21343. PMID: 21712952. Devkota R, et al. Genetics (in press). Volume 219, Issue 1, September 2021. https://doi.org/10.1093/genetics/iyab093 |
| Mutagen | EMS |
| Outcrossed | x10 |
| Made by | Emma Svensk |
| Laboratory | QC |
| Reference | Svensson, E., Olsen, L., Mörck, C., Brackmann, C., Enejder, A., Faergeman, N. J. and Pilon, M. (2011). The adiponectin receptor homologs in C. elegans promote energy utilization and homeostasis. PLoS ONE 6(6):e21343 Devkota, R., Kaper, D., Bodhicharla, R., Henricsson, M., Borén, J. And Pilon, M. (2021). A genetic titration of membrane composition in Caenorhabditis elegans reveals its importance for multiple cellular and physiological traits. Genetics (in press). https://doi.org/10.1093/genetics/iyab093 |
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