Strain Information
| Name | PT3406 View On Wormbase |
|---|---|
| Species | C elegans |
| Genotype | nekl-4(my51[nekl-4::mNeonGreen]) III; him-5(e1490) V. |
| Description | mNeonGreen tag inserted into endogenous nekl-4 locus by CRISPR/Cas9 engineering. Very faint mNeonGreen expression in the dendrites, soma, and axons of all ciliated neurons. Reference: Power KM, et al. PLoS Genet. 2020 Oct 16;16(10):e1009052. PMID: 33064774 |
| Mutagen | Crispr/Cas9 |
| Outcrossed | x3 |
| Made by | Kaiden Power |
| Laboratory | PT |
| Reference | Power KM, Akella JS, Gu A, Walsh JD, Bellotti S, Morash M, Zhang W, Ramadan YH, Ross N, Golden A, Smith HE, Barr MM, O'Hagan R. Mutation of NEKL-4/NEK10 and TTLL genes suppress neuronal ciliary degeneration caused by loss of CCPP-1 deglutamylase function. PLoS Genet. 2020 Oct 16;16(10):e1009052. doi: 10.1371/journal.pgen.1009052. PMID: 33064774; PMCID: PMC7592914. |
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