Laboratory Information
| Name | PT View on WormBase |
|---|---|
| Allele designation | my |
| Head | Maureen M Barr |
| Institution | Rutgers University, Piscataway, NJ |
| Address | Rutgers University 145 Bevier Road PIscataway 08854 United States |
| Website | http://lifesci.rutgers.edu/barrlab/ |
| Gene classes | cil nphp stam nph |
Strains contributed by this laboratory
| Strain | Genotype | Species | Description |
|---|---|---|---|
| EM938 | pdfr-1(bx142) III; him-5(e1490) V. | C. elegans | Male leaving assay defective (Las), lethargic, hypereversal. Reference: Barrios, A, et al. Nat Neurosci. 2012 Dec;15(12):1675-82. |
| PT1194 | klp-6(my8) III; him-5(e1490) V. | C. elegans | Him. |
| PT1443 | inpp-5K(my15) III; him-5(e1490) V. | C. elegans | Spermatogenesis abnormal with small brood size. PKD-2::GFP ciliary localization defective. Maintain at 20 C. inpp-5K formerly known as cil-1. Reference: Bae Y, et al. 2009 Curr Bio 19(19):1599-607. |
| PT2193 | eat-4(n2474) III; him-5(e1490) V. | C. elegans | Defective in male sex drive regulation. Reference: Nat Neurosci. 2012 Dec;15(12):1675-82. |
| PT2248 | pdf-1(tm1996) III; him-5(1490) V. | C. elegans | Male leaving assay defective (Las), lethargic, hypereversal. Reference: Barrios, A, et al. Nat Neurosci. 2012 Dec;15(12):1675-82. |
| PT2351 | him-5(e1490) V; myEx741. | C. elegans | myEx741 [pdfr-1p(3kb)::NLS::RFP + unc-122::GFP]. Him. Pick RFP+ and GFP+ to maintain. Reference: Barrios A, et al. Nat Neurosci. 2012 Dec;15(12):1675-82. |
| PT3406 | nekl-4(my51[nekl-4::mNeonGreen]) III; him-5(e1490) V. | C elegans | mNeonGreen tag inserted into endogenous nekl-4 locus by CRISPR/Cas9 engineering. Very faint mNeonGreen expression in the dendrites, soma, and axons of all ciliated neurons. Reference: Power KM, et al. PLoS Genet. 2020 Oct 16;16(10):e1009052. PMID: 33064774 |
| PT3562 | sid-2(my95[sid-2::mScarlet]) III; him-5 (e1490) V; myIs4. | C. elegans | myIs4 [pkd-2p::pkd-2::GFP + unc-122p::GFP]. Phenotypically normal. sid-2::mScarlet is functional in environmental RNAi. Reference: Nikonorova IA, et al. Curr Biol. 2022 Mar 19;S0960-9822(22)00396-7. PMID: 35334227 |
| PT442 | klp-6(sy511) III; him-5(e1490) V. | C. elegans | Males Lov and response defective. Mislocalizes pkd-2::GFP in cilia. sy511 contains a nonsense mutation in exon 10 (C-T transition = Q706stop). |
| PT501 | flp-8(pk360) X. | C. elegans | Reference: Liu T, et al. J Neurosci. 2007 Jul 4;27(27):7174-82. |
| PT505 | flp-20(pk1596) X. | C. elegans | |
| PT559 | nphp-1(ok500) II; him-5(e1490) V. | C. elegans | Superficially WT. |
| PT709 | nphp-4(tm925) him-5(e1490) V. | C. elegans | Superficially WT. |
| PT8 | pkd-2(sy606) IV; him-5(e1490) V. | C. elegans | Males are response and location-of-vulva defective. pkd-2(sy606) is a 2396 bp deletion (8388 to 5942 in YAC Y73F8A); mutant protein is predicted to contain the N-terminal portion of the protein midway through the first predicted transmembrane region. |
| PT830 | nphp-1(ok500) II; nphp-4(tm925) him-5(e1490) V. | C. elegans | Male mating response defect. |
Alleles contributed by this laboratory
| Allele | Type | DNA Change | Protein Change |
|---|---|---|---|
| my8 | Allele | deletion | |
| my15 | Allele |