Strain Information
| Name | PMD1 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | fem-1(hc17) IV; dal-1(dt2300) |
| Description | Temperature-sensitive. Maintain at 15C. Homozygous double mutant is sterile at 25C. Intestinal morphology defects. Reference: Wang C, et al. Nat Commun. 2017 Dec 22;8(1):2270. |
| Mutagen | No mutagen |
| Outcrossed | x2 |
| Made by | Juan Jamarillo |
| Laboratory | TX |
| Reference | Wang C, Niederstrasser H, Douglas PM, Lin R, Jaramillo J, Li Y, Olswald NW, Zhou A, McMillan EA, Mendiratta S, Wang Z, Zhao T, Lin Z, Luo M, Huang G, Brekken RA, Posner BA, MacMillan JB, Gao J, White MA. Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan. Nat Commun. 2017 Dec 22;8(1):2270. doi: 10.1038/s41467-017-02332-3. |
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