Strain Information
| Name | PHX945 View On Wormbase |
|---|---|
| Species | C.elegans |
| Genotype | nish-1(syb767) IV; sybIs62. |
| Description | sybIs62 [NISH-1::EGFP::3xFLAG + unc-119(+) + myo-2p::mCherry]. Transgene rescues nish-1(syb767) rilemenidine-induced longevity, rilemenidine-induced heat resistance, and rilemenidine-induced healthspan (body bends). Reference: Bennett DF, et al. Aging Cell. 2023 Feb;22(2):e13774. doi: 10.1111/acel.13774. PMID: 36670049. |
| Mutagen | |
| Outcrossed | x0 |
| Made by | Pedro De Magalhaes |
| Laboratory | LSD |
| Reference | Rilmenidine extends lifespan and healthspan in Caenorhabditis elegans via a nischarin I1-imidazoline receptor Dominic F. Bennett, Anita Goyala, Cyril Statzer, Charles W. Beckett, Alexander Tyshkovskiy, Vadim N. Gladyshev, Collin Y. Ewald, João Pedro de Magalhães First published: 20 January 2023 https://doi.org/10.1111/acel.13774 |
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