Strain Information

Name PHX945   View On Wormbase
Species C.elegans
Genotypenish-1(syb767) IV; sybIs62.
DescriptionsybIs62 [NISH-1::EGFP::3xFLAG + unc-119(+) + myo- 2p::mCherry]. Transgene rescues nish-1(syb767) rilemenidine-induced longevity, rilemenidine-induced heat resistance, and rilemenidine-induced healthspan (body bends). Reference: Bennett DF, et al. Aging Cell. 2023 Feb;22(2):e13774. doi: 10.1111/acel.13774. PMID: 36670049.
MutagenNo mutagen
Outcrossedx0
Made byPedro De Magalhaes
Laboratory LSD
Reference Rilmenidine extends lifespan and healthspan in Caenorhabditis elegans via a nischarin I1-imidazoline receptor Dominic F. Bennett, Anita Goyala, Cyril Statzer, Charles W. Beckett, Alexander Tyshkovskiy, Vadim N. Gladyshev, Collin Y. Ewald, João Pedro de Magalhães First published: 20 January 2023 https://doi.org/10.1111/acel.13774
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