Strain Information
| Name | PHX6073 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | tol-1(syb6073[Q712A,Y713A,G714A,N715A]) I. |
| Description | Reduced brood size; high rates of embryonic and larval arrest. CRISPR/Cas9-engineered mutation of residues that mediate interaction with TOL-1 receptor in development. Reference: Carmona-Rosas G, et al. bioRxiv 2023.05.04.539414; doi: https://doi.org/10.1101/2023.05.04.539414. |
| Mutagen | No mutagen |
| Outcrossed | x0 |
| Made by | SunyBiotech |
| Laboratory | KRA |
| Reference | Carmona-Rosas, Li, Smith et al. "Structural basis and functional roles for Toll-like receptor binding to Latrophilin adhesion-GPCR in embryo development." bioRxiv (2023) doi: https://doi.org/10.1101/2023.05.04.539414 |
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