Strain Information

Name PE868   View On Wormbase
Species C. elegans
Genotypepink-1(ok3538) II; feIs5 X.
DescriptionfeIs5 [sur-5p::luciferase::GFP + rol-6(su1006)] X. Rollers. Strain expresses firefly (Photinus pyralis) luciferase (lacking the peroxisome tagging signal) fused in-frame to GFP(S65C) in the pink-1(ok3538) mutant background. It is rendered bioluminescent when it ingests D-luciferin. References: Lagido, C, et. al. (to be submitted to bioRxiv). Novel HTS platform for the identification of drugs active in the modulation of mitochondrial function in age-related diseases.
MutagenNo mutagen
Outcrossedx1
Made byCristina Lagido
Laboratory PE
Reference Lagido C 2018. In vivo luminescent ATP C. elegans sensor strains for drug discovery in age-related diseases – an update. EMBO workshop. C. elegans development, cell biology and gene expression. Barcelona, Spain, 13-17th Lagido, Cristina., McLaggan, Debbie., & Glover, L. A.( 2015). An in vivo sensor of mitochondrial function in C. elegans for toxicity screening and repositioning of drugs presented in International Worm Meeting. Lagido, C, et. al. (to be submitted to bioRxiv). Novel HTS platfo
Sign in or register an account if you want to order this strain.