Strain Information
| Name | PE867 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | pink-1(ok3538) II; feIs4 V. |
| Description | feIs4 [sur-5p::luciferase::GFP + rol-6(su1006)] V. Rollers. Strain expresses firefly (Photinus pyralis) luciferase (lacking the peroxisome tagging signal) fused in-frame to GFP(S65C) in the pink-1(ok3538) mutant background. It is rendered bioluminescent when it ingests D-luciferin. References: Lagido, C, et. al. (to be submitted to bioRxiv). Novel HTS platform for the identification of drugs active in the modulation of mitochondrial function in age-related diseases. |
| Mutagen | No mutagen |
| Outcrossed | xx1 |
| Made by | Cristina Lagido |
| Laboratory | PE |
| Reference | Lagido, C, et. al. (to be submitted to bioRxiv). Novel HTS platform for the identification of drugs active in the modulation of mitochondrial function in age-related diseases. Lagido C 2018. In vivo luminescent ATP C. elegans sensor strains for drug discovery in age-related diseases – an update. EMBO workshop. C. elegans development, cell biology and gene expression. Barcelona, Spain, 13-17th June 2018. (Oral presentation) Lagido, Cristina., McLaggan, Debbie., & Glover, L. A.( 2015). An |
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