Strain Information

Name OH14420   View On Wormbase
Species C. elegans
Genotypepals-22(ot811) III; otIs381 V; otEx6761.
DescriptionotIs381 [ric-19p(prom6)::2xNLS::GFP + elt-2::DsRed] V. Pan-neuronal nuclear GFP expression. otEx6761 [pals-22(+) + ttx-3p::mChOPTI]; derived from PCR fragment containing the genomic pals-22 locus. pals-22(ot811) mutant shows transgene-silencing phenotype; otEx6761 rescues ot811 and restores otIs381 expression at wild-type levels. Reference: Stefanakis N., Carrera I., Hobert O. Neuron. 2015 Aug 19;87(4):733-50. Leyva-Díaz E, et al. Genetics (2017), 207(2):529-545.
MutagenNo mutagen
Made byEduardo Leyva-Diaz
Laboratory OH
Reference Leyva-Díaz E, Stefanakis N, Carrera I, Glenwinkel L, Wang G, Driscoll M, Hobert O. Silencing of repetitive DNA is controlled by a member of an unusual Caenorhabditis elegans gene family. Genetics (2017), 207(2):529-545.
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