Strain Information
| Name | OEB800 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | tmem-107(oq100) I. |
| Description | F39B2.9/TMEM-107 has been shown to control the localization of 4 peripheral ciliary transition zone proteins. tmem-107(oq100); nphp-4(tm925) double mutants display ultra-structural malformations in ciliary transition zones, and exhibit sensory abnormalities including roaming, chemoattractant, and dye-filling defects. TRAM-1::tdTomato leaks into cilia in oq100 mutants. Genotyping primers: Forward cgcggttcttcttgtttctt, Reverse wildtype gagatcgagacggcgacg, Reverse oq100 gaaaaacaacgtggaagtcca. Reference: Lambacher NJ, et al. Nat Cell Biol. 2016 Jan;18(1):122-31. |
| Mutagen | Crispr/Cas9 |
| Outcrossed | x2 |
| Made by | Nils Lambacher |
| Laboratory | OEB |
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