Strain Information

Name OD4027   View On Wormbase
Species C. elegans
GenotypeltSi448 II; unc-119(ed3) III; ltIs37 csr-1(tm892) IV.
DescriptionltSi448 [csr-1p::GFP::csr-1(re-encoded; GFP inserted after aa #5 of isoform b) + Cbr-unc-119(+)] II. ItIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV. The csr-1 coding sequence in the transgene was re-encoded for RNAi-resistance (see Gerson-Gurwitz A, et al. Cell. 2016, Supplementary Figure S3A). [NOTE: it is not known if unc-119(ed3) is still present in the background of this strain.] Derived from strain OD1764; transgene rescues csr-1, so the balancer is not needed to maintain transgenic strain. Reference: Gerson-Gurwitz A, et al. Cell. 2016 Apr 7;165(2):396-409.
Made byAdina Gerson-Gurwitz
Laboratory OD
Reference Gerson-Gurwitz, Adina et al. “A Small RNA-Catalytic Argonaute Pathway Tunes Germline Transcript Levels to Ensure Embryonic Divisions.” Cell 165 (2016): 396-409. Print.
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