Strain Information
| Name | NK3241 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | let-2(qy289[let-2 (G1287D)::mNG]) X. |
| Description | Endogenously tagged temperature sensitive glycine substitution mutant allele (b246) of let-2. Tagged with mNG at the C-terminus. Temperature sensitive embryonic lethal. Grows at 15C, 20C. Lethal at 25C (embryonic). See also CGC DH246. Reference: Srinivasan S,et al. J Cell Biol. 2025 224(6):e202412118. doi:10.1083/jcb.202412118 PMID: 40100062. |
| Mutagen | Crispr/Cas9 |
| Outcrossed | x0 |
| Made by | Sherwood Lab |
| Laboratory | NK |
| Reference | Srinivasan S, Ramos-Lewis W, Morais MRPT, et al. A collagen IV fluorophore knock-in toolkit reveals trimer diversity in C. elegans basement membranes. J Cell Biol. 2025;224(6):e202412118. doi:10.1083/jcb.202412127 |
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