Strain Information
| Name | NF4629 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | vha-7(tk181) IV. |
| Description | Short lifespan. vha-7(tk181) is a point mutation isolated as a suppressor of sqv-5(k175). tk181 represses the formation of tubular lysosome. Reference: Shibata Y, et al. Scientific Reports. In press. |
| Mutagen | EMS |
| Outcrossed | x2 |
| Made by | Yuki Tanaka/ Shunsuke Mohri |
| Laboratory | NF |
| Reference | Endogenous chondroitin extends lifespan by inhibiting VHA-7-mediated tubular lysosome formation Yukimasa Shibata, Yuri Tanaka, Shunsuke Mori, Kaito Mitsuzumi, Shion Fujii, Hiroyuki Sasakura, Yuki Morioka, Kenji Sugioka, Kosei Takeuchi & Kiyoji Nishiwaki Scientific Reports in press |
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