Laboratory Information
Name | NF View on WormBase |
---|---|
Allele designation | tk |
Head | Kiyoji Nishiwaki |
Institution | Kwansei Gakuin University, Sanda, Japan |
Address | Kwansei-Gakuin University School of Science and Technology 2-1 Gakuen, Dept. of Bioscience Sanda 669-1337 Japan |
Website | http://sci-tech.ksc.kwansei.ac.jp/~nishiwaki/ |
Gene classes | cogc phal saf |
Strains contributed by this laboratory
Strain | Genotype | Species | Description |
---|---|---|---|
NF1226 | mig-22(tk69) III/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III). | C. elegans | mig-22(tk69): DTC migration defect and maternal effect embryonic lethal. Heterozygotes are WT with pharyngeal GFP signal. Homozygous hT2[bli-4 let-? qIs48] are inviable. |
NF1684 | cogc-3(k181) I. | C. elegans | Distal tip cell migration defective. Growth delay. Protruding vulva. |
NF1796 | mig-22(k185) III. | C. elegans | Long lifespan and healthspan. mig-22(k185) is a gain-of-function allele that increase endogenous chondroitin and suppress the gonad migration defect of mig-17(k174). Reference: Shibata Y, et al. Sci Rep. 2024 Feb 27;14(1):4813. doi: 10.1038/s41598-024-55417-7. PMID: 38413743. |
NF196 | sqv-5(k172) I. | C. elegans | DTC migration defect. |
NF198 | mig-17(k174) V. | C. elegans | Distal tip cell migration defective. |
NF199 | sqv-5(k175) I. | C. elegans | DTC migration defect. |
NF299 | cogc-1(k179) I. | C. elegans | Distal tip cell migration defective. Growth delay. Protruding vulva. |
NF317 | mig-23(k180) X. | C. elegans | Distal tip cell migration defective. Tc1 insertion mutant. Spontaneous mutant with ventral white patch phenotype. |
NF4209 | tlk-1(tk158) III/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III). | C. elegans | Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested hT2 aneuploids, and non-GFP tk158 homozygotes (sterile). Homozygous hT2[bli-4 let-? qIs48] inviable. Pick WT GFP and check for correct segregation of progeny to maintain. Reference: Shibata Y, et al. Biol Open. 2019 Jan 17;8(1):bio038448. doi: 10.1242/bio.038448. PMID: 30635266. |
NF4629 | vha-7(tk181) IV. | C. elegans | Short lifespan. vha-7(tk181) is a point mutation isolated as a suppressor of sqv-5(k175). tk181 represses the formation of tubular lysosome. Reference: Shibata Y, et al. Scientific Reports. In press. |
NF591 | mig-22(tk24) III. | C. elegans | DTC migration defect. |
NF67 | mig-18(k140) III. | C. elegans | Distal tip cell migration defective. |
NF68 | mig-22(k141) III. | C. elegans | DTC migration defect. |
NF69 | mig-19(k142) II. | C. elegans | Distal tip cell, HSN migration defective. |
NF773 | fbl-1(k201) IV. | C. elegans | Isolated as a dominant suppressor of DTC migration defects of mig-17(k174). The fbl-1(k201) single mutant has weak DTC migration defects. |
NF774 | fbl-1(k206) IV. | C. elegans | Isolated as a dominant suppressor of DTC migration defects of mig-17(k174). The fbl-1(k206) single mutant has weak DTC migration defects. |
NF78 | mig-20(k148) X. | C. elegans | Distal tip cell, HSN, left cc mother cell, QR(d) migration defective. |
NF8 | mig-17(k113) V. | C. elegans | Distal tip cell migration defective. |
NF963 | fbl-1(tk45) IV/nT1 [qIs51] (IV;V). | C. elegans | Heterozygotes are WT and GFP+. nT1[qIs51] is probably homozygous lethal. qIs51 is an insertion of ccEx9747 with markers: myo-2::GFP expressed in the pharynx throughout development, pes-10::GFP expressed in the embryo, and a gut promoter F22B7.9::GFP expressed in the intestine. fbl-1(tk45) homozygotes are Dpy, Sterile and are Distal Tip migration defective. |
Alleles contributed by this laboratory
Allele | Type | DNA Change | Protein Change |
---|---|---|---|
tk69 | Allele | deletion | |
tk24 | Allele | substitution | splice_site |
tk45 | Allele |