Strain Information
| Name | MT6241 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | acr-2(n2420) X. |
| Description | Gain-of-function allele. Spontaneous shrinker, jerky, Unc. G925A, V309M in the pore lining domain. References: Jospin M, et al. PLoS Biol. 2009 Dec;7(12):e1000265. Stawicki TM, et al. Curr Biol. 2011 May 24;21(10):883-8. |
| Mutagen | EMS |
| Outcrossed | x1 |
| Made by | Yishi Jin |
| Laboratory | CZ |
| Reference | Jospin M, Qi YB, Stawicki TM, Boulin T, Schuske KR, Horvitz HR, Bessereau JL, Jorgensen EM, Jin Y. A neuronal acetylcholine receptor regulates the balance of muscle excitation and inhibition in Caenorhabditis elegans. PLoS Biol. 2009 Dec;7(12):e1000265. doi: 10.1371/journal.pbio.1000265. Epub 2009 Dec 22. Stawicki TM, Zhou K, Yochem J, Chen L, Jin Y. TRPM channels modulate epileptic-like convulsions via systemic ion homeostasis. Curr Biol. 2011 May 24;21(10):883-8. doi: 10.1016/j.cub.2011.03. |
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